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These cell type specific variations differ between separate differentiation stages as has been shown with the cells of the hemapoietic system, using stem cells, progenitor cells, and differentiated cells of the myeloid and erythroid lineages [ 19].
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The above-defined "animal" state of D. discoideum during growth and aggregation, completely separated from differentiation, is the first asset of D. discoideum as a model for eukaryotic cells.
Furthermore every patient of group IV (cuff arthropathy) had a massive rotator cuff tear so that the two groups cannot be strictly separated and differentiation between the two groups is floating.
Monocytes from circulation that enter the kidney in response to inflammation undergo separate pathways of differentiation into classically activated M1 macrophages or the alternative M2 phenotype.
Delta-Notch signalling is a form of cell cell communication, helping a group of similar cells to integrate contextual information and steer down separate pathways of differentiation.
A comparison of traditional (based on the island model) and coalescence-based analytical approaches that can separate overall genetic differentiation into reciprocal migration rates [ 33, 34] should be able to illuminate the roles of migration and drift in establishing patterns of genetic differentiation among populations [ 8].
These pools are spatially separated and genetic differentiation between the rock pool populations is strong [28].
In contrast, Pten deficient tumors exhibited extensive nodularity with neuronal differentiation separated by focal areas of intense staining for proliferation and virtually absent apoptosis.
Compared to tumors from control mice, SmoA1+/−; Pten +/− tumors exhibited extensive nodularity with neuronal differentiation separated by focal areas of intense staining for proliferation and virtually absent apoptosis.
Th17 and Treg attractors are not as strongly separated, so further differentiation is possible with moderate external stimuli.
Similar heterochronic differentiation separates other closely related species throughout the eucalypt phylogeny, suggesting this process has occurred independently numerous times in eucalypt evolution (Potts and Wiltshire 1997).
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