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Recent studies of bacterial behavior have begun to reveal the molecular logic of this sensory architecture.
This suggests that the sensory architecture mediating certain polymodal behaviors can evolve (Table 2).
Unveiling such mechanisms should enhance our understanding of the evolution of sensory architecture, particularly the emergence of DRG in craniates and subsequent disappearance of RB cells in amniotes.
The species-specific activities of Six1 enhancers, which correlate with the differential onset of Six1 expression in the trunk sensory precursors, could be the genetic basis for the different sensory architecture in frogs and mice.
The study provided evidence that early appearance of SIX1 expression, which correlated with mouse Six1 enhancer, is essential for the formation of DRG-dominant system in mice, suggesting that heterochronic changes in Six1 enhancer sequence play an important role in alteration of trunk sensory architecture and contribute to the evolution of the trunk sensory system.
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Gain- and loss-of-function of Six1 was demonstrated by experimental changes in intra- versus extramedullary sensory neurons both in frogs and mice, suggesting the conserved function of Six1 in both species despite the different sensory architectures.
Raymond Chandler is peeping out from Price's skull, as well he should be, given such gloomy doings, but in the enormous, cross-sensory architecture of the last three words above, one detects Saul Bellow's vision, too.
We show that SERT expression in glutamatergic thalamocortical axons (TCAs) dictates sensory map architecture.
We previously identified that knockout of SERT in the thalamic neurons blocks 5-HT uptake by their thalamocortical axons, resulting in excessive 5-HT signaling that impairs sensory map architecture.
Our present data show that cell division in the adult wing is continued to complete the sensory neuronal architecture.
Identifying the mechanism of disappearance of RB cells might produce further evidence to understand the evolution of sensory neuron architecture.
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