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In this mutant, the Ssy1 permease-like amino-acid sensor responsible for the activation of several amino acid permeases (such as AGP1, BAP2, GNP1).
By this stage it was known that hypoxic stabilisation of HIF-α subunits leads to their accumulation, but the oxygen sensor responsible for regulating this process remained elusive.
The DNA sensor responsible for caspase-1 activation in abortively infected T cells appears to be IFI16 (Monroe et al., 2014).
Toll-like receptors (TLRs) are a kind of specialized sensor responsible for recognizing molecular patterns of pathogens and bridging innate and adaptive immunity by activation of antigen-presenting cells such as dendritic cells and macrophages.
Our recent work shows that activity of the AMP-activated protein kinase (AMPK), the bio-energy sensor responsible for maintaining cellular energy homeostasis in all eukaryotic cells, plays an important role in the initiation of axonal growth.
In addition, because all of our mutations targeted residues on TMEM16A, our results lend further support to the notion that the TMEM16A polypeptide itself encodes the calcium sensor responsible for channel activation.
Similar(53)
It currently houses the electrical controls, including the sensors responsible for starting the light.
Glucokinase (GK) has been identified as a glucose-sensor responsible for detecting such changes both within the brain and the periphery.
So far, two cytosolic DNA sensors responsible for type I IFN induction have been discovered.
The switch elements act as nucleotide sensors responsible for communication between the nucleotide biding pocket and the actin binding sites.
cGAS and TLR9 have been reported to be the DNA sensors responsible for the recognition of adenoviral DNA leading to the induction of type I IFN production [ 15, 16].
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