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The authors demonstrated using inside-out patches of HEK-293 cells expressing TRPA1 that short polyphosphates (2 65 residues) are required for sensitizing this channel to pungent chemicals and for preserving the protein in the functional conformation.
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Furthermore, re-introduction of ectopically expressed bid (Fig. 1 D) was able to re-sensitize this clone to Fas-induced caspase activation and apoptosis (Fig. 1 E), indicating that the reduction in caspase activity after death receptor activation was due to the lack of Bid expression.
New exercises are performed to sensitize this part of the body.
In contrast, a deoR knock-out sensitized this strain to the drug, resulting in 97% killing after 3 hours.
mTORC1 inhibitor did not induce any beneficial effect on CML stem cells and conversely to PI3K inhibitors that sensitize this TKI-resistant population to nilotinib.
This clearly shows that there is a need to sensitize this population to seek medical assistance as soon as symptoms of dysphagia start to develop, to improve the treatment outcomes.
Interestingly, these authors also observed that S. cerevisiae Δ sod1 and Δ yap1 were hypersensitive to exogenous gliotoxin, suggesting that a deficient oxidative stress response sensitizes this organism to gliotoxin.
This compound is capable of sensitizing the TiO2 surface and efficiently converting the sunlight into electricity.
This indicated the potential of the theses compounds in sensitizing the tissues for the external insulin.
This is accompanied by a drastic reduction in p2l and 14-3-3σ 14-3-3σ 14-3-3σ thereby significantly sensitizing the cells to aproteins.
This could sensitize the liver parenchyma in this zone to metabolic disorders, resulting in lipid accumulation (Kelly 1993; MacLachlan and Cullen 1995; Parkinson 1996).
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