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The unadjusted data indicate the relevance of multiple allergies for the highly atopic child, whereas the adjusted data demonstrate the role of a single sensitizing allergen and its significance for the further sensitizing process during childhood.
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One might argue that in our region, with high birch pollen counts during a limited period at spring time, sensitization to birch early in life could be a "driving force" for the sensitizing process to inhalant allergens.
In our region birch allergen, seems to precede, and may even be driving the further sensitizing process which may be considered for further studies on therapeutic interventions.
On the other hand, the reduced differential activation in fibromyalgia patients may also be a result of the chronic painful condition; e.g in CNS (central sensitizing processes, alterations in function of neuromatrix of pain in the brain or in descending inhibition) [ 35- 38] and/or in muscle [ 9- 11].
Detailed Description of Processes during Heating.
It is during the maturation process, not during fermentation.
The value of S-1 in pancreatic cancer is not limited to its sensitizing effect during CRT.
This can occur if an RhD negative pregnant woman has a sensitizing event during her pregnancy that causes the development of anti-D antibodies [ 2].
Nevertheless, it must be appreciated that there is still a risk of alloimmunization of the mother either from transfusion of allogenic blood or a sensitizing event during pregnancy.
Our strategy of producing a sensitized Eu chelate in situ allows us to use a relatively inexpensive, commercially available bifunctional ligand for conjugation to the biomolecular probe and obviates any possible complications involving the sensitizing moiety during conjugation.
In conclusion rAra h 1, 2, and 3 were the prevalent sensitizing allergens during the first years of life in Italian patients with sIgE to peanuts ("genuine" allergy); in contrast rAra h 9 and 8 were mainly involved in school-age children and adolescents with pollen allergy ("secondary" sensitization).
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