Exact(1)
The already existing sensitizing model is based on biological experiments including measurement of caspase-3/-7 andivity and cytochrome c release under varying conditions, such as only TNFα, only Fas ligand and combination of both, and reproduces these data [20].
Similar(59)
The developed model is connected with a TNFα/Fas ligand sensitizing model [20] and with an NF-κB model [21] to reflect the complex crosstalks in this system.
This SGS model is sensitized to non-equilibrium flows, preserving the anisotropic characteristics of turbulence; this aspect makes it a subtle means to simulate the flow with strong recirculating and separation.
(4) Aquifer pore volume used for numerical aquifer model was sensitized upon until satisfactory pressure and saturation match was obtained. .
OA challenge to passively sensitized guinea pigs was carried out by the same method used in actively sensitized model.
An allergic rhinitis model was successfully established by sensitizing mice with intraperitoneal OVA and then challenging them with an intranasal OVA drip [ 26].
This model was fully integrated with our model of TNFα/Fas ligand sensitizing as well as with a published NF-κB-model.
Many insulin sensitizing drugs are PPARG agonists [ 38].
Multiple logistic regression models were used for calculations of odds ratios (ORs) and CI between specific sensitizing allergen at 4 years in relation to sensitization at 8 years.
Interestingly, the structure of the sensitizing model allows also simulating different cell types.
Many sensitizing agents have been developed in a variety of tumor cell models.
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