Sentence examples for sensitizing compounds from inspiring English sources

As an example we took skin sensitizing compounds as one class and irritating compounds as another.

It is desirable that the RCM candidate materials do not contain any leachable irritating or sensitizing compounds.

Of note, our Prediction Signature is able to predict the potency of sensitizing compounds, as defined by the LLNA.

We have modified an existing hanging drop 3D-microtissue technology (Insphero, AG) to develop a high content screen to interrogate potential radiation sensitizing compounds.

While these experiments have resulted in successful predictions (data not shown), it is our experience that sensitizing compounds differ greatly in their induced gene expression profile, as can be seen in Figure 3D.

The here studied fulleropyrrolodine iodide salt exerts high bactericidal efficacy primarily against gram-positive bacteria, not surprising considering that most of the sensitizing compounds effectively penetrate gram-positive and fungal cells (Malik et al. 1992).

A comprehensive search of the literature revealed that five of the compounds (camptothecin, genistein, paclitaxel, wortmannin, and thapsigargin) had been previously reported as TRAIL synergizers [12] [16] and two (YC-1 and APDC) are previously unidentified TRAIL-sensitizing compounds (Table 1).

However, CD40-stimulated CLL cells could not be sensitized to Compound A with ABT-737, indicating that induction of pro-survival Bcl-2 family members by CD40 stimulation does not mediate resistance to Compound A in CLL cells.

ABT-737, which specifically inhibits Bcl-XL and its close relative Bcl-2, could not sensitize to Compound A, arguing against a contribution of increased levels of Bcl-XL in resistance against smac mimetics.

Moreover, KB-3-1 cells were sensitized by compound 3 to vincristine in a way that it reached much lower IC50 values than observed in KB-C-1 cells treated with the combination: the IC50 value was 0.67 nM (without compound 3: 2.84 nM) in case of KB-3-1, white it was ca. 10 times higher, 6.78 (without compound 3: >50 nM) in case of the MDR subline KB-C-1.

Currently, we sought to determine if alkylamides, like other chemesthetic compounds, evoke sensitizing and/or desensitizing patterns of sensation that are ISI dependent.