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The model has to show no caspase-3 activation after TNFα, medium caspase-3 activation after Fas ligand and high caspase-3 activation after TNFα/Fas ligand sensitizing as shown in [20] for wildtype hepatocytes.

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Note that both receptor and psychophysical thresholds can be strongly sensitized with capsaicin treatment, as shown here.

Furthermore, these cells were highly sensitized to heat-induced apoptosis as shown by an increased percentage of Annexin-V staining and DEVDase activity.

In our opinion this difference, however, reflects the small number of animals in each experimental group, which reduced the statistical power of the analysis, and the lower effectiveness of minocycline in sensitizing PrP peptides to protease hydrolysis, as shown in cell-free tests [7].

As shown in Figure 5A, sensitized FcγRIIb KO mice had significantly higher RWE-specific IgE levels when compared to WT mice.

While single knockdown of either c-Cbl or Cbl-b had some effect on sensitizing to death, double knockdown was consistently more effective, as shown in Fig 2C.

It has been proposed that the pharmacological suppression of cellular antioxidants or elevation of ROS levels can sensitize tumor cells to doxorubicin [ 28, 29] as shown here by combination treatment with TM.

As shown in Figure 3B, downregulation of CIP2A sensitized resistant MCF-7 cells to bortezomib-induced apoptosis.

As shown in Figure 8a, treatment with LiCl sensitized MCF10A cells to PI (MG132 1  μM; see Figure 5).

As shown in figure 1C, the expression of Bax sensitized the A15A5 cells to apoptosis induced by both FasL and GrB while apoptosis was inhibited by the presence of Bcl-2 under the same conditions.

As shown in Table 3, arthritis occurred in all animals sensitized with complete Freund's adjuvant.

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