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Furthermore, not only tumor-associated pathologies show ER-associated c-Fos: in spinal cord of rats sensitized to develop experimental allergic encephalomyelitis in which positive reactive gliosis is promoted [31], c-Fos expression is also increased and ER-associated (Fig. S2).
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Sheep sensitized to HDM develop allergen-specific IgE responses, inflammation of the airways following airway allergen challenge that includes profound eosinophilia, airway epithelial mucus hypersecretion, airway wall remodelling and early and late-phase asthmatic responses and AHR following airway allergen challenge [ 22– 22].
Patients who are sensitized to these can develop symptoms after ingestion of seemingly unrelated foods.
On first exposure to the allergen, the person becomes sensitized to it that is, develops antibodies and specific T cells to the allergen.
It is not known what proportion of individuals who are sensitized to beryllium will progress to develop CBD.
However, as we previously observed [ 11], mice that are exposed to BPA, but not sensitized to OVA did not develop an asthma phenotype, suggesting that prenatal BPA exposure enhances the allergic component of asthma pathogenesis.
The first example is occupational asthma, especially that caused by laboratory animal allergy, where 25 30% of workers who are sensitized to laboratory animal allergens develop symptoms within 1 year of beginning work (Bush et al. 1998).
After a few weeks of infestation, the child becomes sensitized to the parasite and develops an itchy rash, particularly on the hands and armpits.
But one industry official said the company would make the case that people need to be sensitized to an allergen over time in order to develop allergic reactions.
Kids who are sensitized to certain foods, however, are more likely to develop full-blown allergies to them in the future.
Many subjects are sensitized to Japanese cedar pollen but do not develop allergic rhinitis (AR).
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