Sentence examples for sensitized responses from inspiring English sources

Initiation of sensitization may require single toxic or multiple subtoxic exposures, but subsequent elicitation of sensitized responses can involve low or nontoxic levels.

Intra-accumbal Tat1 72 alters acute and sensitized responses to cocaine.

The context in which a drug is experienced can significantly influence both acute and sensitized responses to the drug [ 47, 48].

For example, intra-VTA injections of SCH 23390 blocked both the cocaine-induced increase in extracellular dopamine in the NAc and the development of sensitized responses [ 35].

However, at metaplastically-primed physiological limits, sensitized responses will change direction (oscillate) with each successive dose [ 97, 186, 187], thereby potentially promoting recovery from disease if chosen for salience and properly timed[ 11].

Weight-bearing asymmetry in MIA-injected rats is coincident with sensitized responses of joint C fiber and Aδ fiber nociceptors (14) and is associated with increased CGRP expression in joint afferents (8, 9).

For example, in a skin test, if a rash develops soon after applying a little milk with a prick, that's considered evidence of a sensitized response to milk.

However, a sensitized response is not enough to make a diagnosis of milk allergy — it's only one small part of a host of reactions that make up a food allergy, says Assa'ad, who served on the institute's expert panel.

Although by day 4, both WT and GASP-1 KO mice displayed a sensitized response, the GASP-1 KO response was significantly blunted on all days (Fig. 2B,D **p<0.01 **p<0.01 and ***p<0.001, WT versus GASP-1 KO).

These behavioural studies show the PSD95 SH3 domain has an essential and specific role in the sensitized response to tissue inflammation.

Blocking this recruitment with either a mutation or a peptide competitor abrogates the anticipated sensitized response, as does administration of a PI(3 K-C2α inhibitor.