Sentence examples for sensitized human from inspiring English sources

Blocking GPx1 activity sensitized human astrocytes towards (SKI+TMZ -induced ER SKI+TMZ -induceddERth.

In marked contrast, even low concentrations of TRAIL strongly sensitized human hepatocytes to doxorubicin-induced cell death, and vice versa.

Thus, the radiation survival curves obtained by the colony formation assay showed that BI 2536 pretreatment sensitized human medulloblastoma cells to ionizing radiation.

Our results show that pretreatment with salirasib sensitized human hepatocarcinoma cell lines, but not normal human hepatocytes, to TRAIL-induced apoptosis.

Finally, siRNA-mediated silencing of ERCC1 (excision repair cross complementing group 1) sensitized human colorectal cancer cells to oxaliplatin-induced cell death [ 52].

In another related study, EGCG sensitized human prostate carcinoma LNCaP cells to TNF-related apoptosis-inducing ligand-induced apoptosis and synergistic inhibition of the biomarkers of angiogenesis and metastasis [ 70].

As a result, rotenone failed to sensitize human PBMC to TRAIL-induced apoptosis, indicating that the sensitizing effect of rotenone is tumor cell specific.

We have previously shown that loss of UNG expression sensitizes human cancer cells to pemetrexed and that UNG expression predicts pemetrexed sensitivity in experimental models of human cancer.

YAP depletion further sensitizes human cancer cells to anti-cancer agents, such as cisplatin or the EGFR tyrosine kinase inhibitor erlotinib[118], and increased YAP/TAZ levels correlate with taxol and cisplatin resistance[100, 119, 120].

We have also shown that our designed artificial microRNAs (amiRs) could efficiently target XRCC4 (an essential factor for NHEJ) or XRCC2 (an essential factor for HRR) and sensitize human tumor cells to X-rays.

The present study was designed to investigate the ability of celecoxib, a selective COX-2 inhibitor, to sensitize human head-and-neck cancer cell line, HN5, to radiation, and examine its effects on DNA repair, which may be a potential mechanism of radiosensitization.