However, when we sensitized the mice before the feeding started, we observed significant CD4 T-lymphocyte infiltration into the tissue.
We postulate that the first minimal exposure to the chemical (5 months before admission) sensitized the patient, whereas the second exposure (9 days before admission) triggered the strong immunologic reaction that resulted in hepatotoxicity.
Protection Measures Specialists in food allergy suggest that women with personal or family histories of serious allergies -- not just food allergies -- avoid eating peanuts in pregnancy and while nursing, to reduce the risk of sensitizing children before their immune systems can handle the allergens.
A class he took the year before had sensitized him to the bioethical issues surrounding animal research, and as he worked directly with rats, his interest in the topic grew.
In fact, when peanuts are eaten in pregnancy and lactation, some children may become sensitized to the allergenic proteins before birth or, more likely, through breast milk.
The view of immunological ignorance of the CNS has, however, been in conflict with observations by Medawar and colleagues that an allogenic tissue graft into the brain, which would be tolerated in a naive host, was readily rejected in a recipient which was sensitized to the allo-antigens before the transplantation [ 2].
When that happens, the immune system is suddenly exposed to the things you're eating and the medications you're taking, and it can get chronically turned on or sensitized to new things that it wasn't sensitive to before".
MISO given 30 min before single doses of radiation further sensitized the skin, but for 10 fractions in O2 no MISO sensitization was detected.
Mc Veigh's actions took place in 1995, well before we as a nation became sensitized to terrorism by the events of 9/11/2001.
In each of the sites, the proprietors of the health facilities and their staff were sensitized and trained on the food aid component before they were given the food for distribution.
