Sentence examples for sensitize these types from inspiring English sources

Activation of receptor tyrosine kinases such as EFGFR, ERBB2, and c-MET can promote over-expression of FASN and other genes involved in lipid and sterol biosynthesis, and this may sensitize these types of tumors to FASN inhibition.

Conversely, the expression of HCN2 could sensitize these cells to STS/PKC412.

DAC inhibitors possessing class I inhibitory activity have shown the potential to sensitize many types of tumor cells [33], [34], including CLL [35], to tumor necrosis factor-related apoptosis inducing ligand (TRAIL).

Moreover, its orally bioavailable derivative, ABT-263, has shown potential clinical utility in combination therapies as it has been demonstrated to sensitize tumor types, including colorectal cancer cells, to a range of chemotherapies.

This pathway is all the more interesting that it is known to regulate Mcl-1 trandlatisn and is targeted in this way to sensitize several types of cancer justifying the development of pharmacological PI3K/AKT/mTOR inhibitors [ 10, 19, 25].

In some types of cancers pentoxifylline (PTX) sensitizes these cells to the toxic action of chemotherapeutics drugs such as adriamycin, inducing apoptosis.

"We have shown that cocaine exposure sensitizes these cells and increases their susceptibility to infection".

We found that the initiation of differentiation sensitized these cells to cell death.

It sensitizes these cells to RA mediated growth suppression.

Thus in select cells, PTEN restoration sensitized these cells to the killing effects of radiation [ 34].

Wright and colleagues demonstrate that the HSP90 inhibitor 17-DMAG sensitizes these cells to chemotherapy.