These phenotypes are drastically enhanced by sensitizing the cul-5 mutant background by reducing genetic dosage of the Cul-5 CRL receptor Gustavus (Gus) [13] (JM.K. and P.L., submitted), indicating that Cul-5 acts at least in part through Gus to ensure normal ovarian morphogenesis.
Doses of parthenolide and bortezomib that were capable of sensitizing the two endocrine-resistant breast cancer models to tamoxifen can suppress NF-κB and AP-1 regulated gene expression in combination with tamoxifen.
Doses of parthenolide and bortezomib capable of sensitizing the two endocrine resistant breast cancer models to tamoxifen were capable of suppressing NFκB and AP-1 regulated gene expression in combination with tamoxifen and also increased ER recruitment of the transcriptional co-repressor, NCoR.
Next we evaluated if genipin could sensitize the MX2 cells to menadione toxicity.
In this context, mechanical ventilation with high Vt and zero PEEP would somehow sensitize the lung to systemic bacteremia.
The experiments were designed to sensitize the three-body H + O2 + M → HO2 + M reaction, whose rate is subject to notable uncertainty.
Roughly similar proportions of children were diagnosed as being sensitized to one, two, three or four common inhalant allergens.
Roughly similar proportions of children were diagnosed as being sensitized to one, two, three or four common allergens.
A large UNICEF-supported multimedia awareness-raising campaign, comprising a musical album, a short film and video clips were aired on television during six months, sensitizing the population on the long-denied phenomenon of child trafficking.
Both sera of soya-allergic patients activated the basophils upon incubation with Gly m 4, while cells sensitized with three of the four soya-tolerant patients' sera did not react with Gly m 4 (Fig. 3B).
In fact, IKK2 inhibition also sensitized two of the five remaining TNFR1-expressing MM cell lines (OPM2, KMS-12-BM) analyzed in Figure 1 for TNF-induced cell death.
