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Prolonged β-agonist exposure may also sensitize the function of other pro-contractile receptors in the airways, for example, bradykinin or histamine receptors [ 130,131].
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By inference from other chronic inflammatory conditions, one could argue that a chronic pro-inflammatory environment would be harmful, and could either directly promote age-associated decline in function, sensitize the brain to a second insult or even trigger a proteinopathy.
Since p53 and nuclear factor-κ-gene binding (NF-κB -dependent apoptosis had beeNF-κB -dependentNF-κB -dependent2], it is possible thapoptosistion of UCP2 in hadG2 cell could restore the p53 function therefore to sensitize the cell for apoptosis induction.
It is known that platelet function alters in diabetic subjects, which may sensitize the platelet for stresses to generate thrombi.
These could be trial balloons, meant to sensitize the Israeli public to less far-reaching concessions.
These mechanoreceptors sensitize the anemone to maximally discharge nematocysts.
However, in these studies and others using transient or stable XIAP knockdown, loss of XIAP function sensitized the cells to TRAIL induced apoptosis.
Inhibition of proteasome function by MG-132 sensitized the surviving clonogenic PC-3 cells to the effects of ionizing radiation as shown by the left-shift of the survival curve (Fig. 2).
These results suggest that golvatinib inhibits pericyte function by inhibiting EphB4 and/or Tie2 and sensitizes the lenvatinib-resistant network.
Id3 also sensitizes the sarcoma cell line MG-63 to cisplatin 12. Genetic aberrations of Id3 suggest that it may function as a tumor suppressor.
> The key function of the CAB from the perspective of all the respondents was noted to be that of sensitizing the communities about the research study.
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