The ultimate challenge for developing non-animal test methods for skin sensitization testing will be applying our mechanistic understanding of ACD to the design of predictive in vitro alternative test methods.
Thus, these findings indicate that the trafficking and accumulation of cholesterol in mitochondria is a characteristic feature of many types of cancer and its role in carcinogenesis may be related to the regulation of cell death and chemotherapy sensitization, which will be described below.
It is unlikely that the sensitization thresholds will be known but it is hypothesized that they are higher than the elicitation thresholds.
Thus, a community notification and sensitization component will be included to increase awareness of ultrasound and pregnancy complications directed not only at pregnant women, but for husbands, family, and community leaders.
Finally, based on the theoretical background and the findings in FM, the hypothesis concerning central sensitization in CFS will be unfolded, supported with the present knowledge on CFS.
Most respondents felt behaviour change was possible with sensitization 'If people will be well educated they will follow [the advice]' [FGD mother 35 year old, 2 children, no schooling] or had already occurred due to health workers advice.
In chronic conditions such as osteoarthritis (OA) or rheumatoid arthritis (RA), neural sensitization will not be confined to the periphery.
It is hence expected that the stronger PL from LCs is achieved, the more effective sensitization of Er3+ ions will be acquired.
Few fungi of the >1 million species of fungi thought to exist worldwide have been subjected to the antigenic scrutiny that Aspergillus and a few other common airborne fungi have and it is likely that sensitization to other fungi will be discovered in the future.
Finally, sensitization to HER2-targeted therapy will be evaluated in a limited number of studies.
