Other important sensitization targets are components that contribute to NF-κB activation, which otherwise often impedes efficient elimination of cancer cells [ 14].
Our candidate target sets in Table 3 include all published sensitization targets in Tables 1 and 2. However, with the exception of ATM, inhibiting the published sensitization targets in Tables 1 and 2, blocks only part of the cell survival pathways of the model in tumours containing certain mutations.
The results point to the importance of conditioning to context specific sensitization and targeting memory re-consolidation of conditioning as a paradigm to modify sensitization.
"We need to have gender sensitization activities targeting to different levels... so that people don't experience stigma, whether it is from the decision maker, service provider, or community," suggests Aryal.
The health system should intensify sensitization campaigns targeting especially women in the rural who have poor knowledge and little access to cervical cancer prevention services.
Additional community sensitization activities targeting women and their families may also be helpful to emphasize key instructions about when to take the medicine.
A CBA2I advocacy campaign began in Kenya in 2006 with sensitization efforts targeting key stakeholders in the medical field, such as medical professional associations and Ministry of Health (MOH) stakeholders at the provincial level.
The child psychiatric unit will also need to carry out more sensitization program targeted at primary care providers, teachers, parents and the community at large to further improve detection, treatment and referrals.
(a) This pictogram is a symbol for acute toxicity, skin corrosion/irritation, serious eye irritation, skin sensitization, or specific target organ toxicity (single exposure) according to the GHS [4, 53].
