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This flaw in the way the brain perceives pain has recently led experts to classify this illness as a "central sensitization syndrome".
Many factors contribute to central sensitization syndrome.
A decrease in this pain inhibitory loop is an important component of central sensitization syndrome [ 39].
(Int7) "..like central sensitization syndrome… I don't know what the right term would be that someone reading your guidelines would recognize.
Patient presentation may be complex and involve many different factors such as depression, insomnia or when the condition doesn't fit neatly into one title: "..like central sensitization syndrome… I don't know what the right term would be that someone reading your guidelines would recognize.
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FMS is one of the central sensitization syndromes.
FMS, chronic lethargy syndrome, irritable intestine syndrome, tension type headache, and myofacial pain syndrome are parts of central sensitization syndromes.
The number of tender joints can be influenced by factors other than joint inflammation, including osteoarthritis of the examined joints or pain amplification in central sensitization syndromes, thereby rendering it less reflective of RA disease activity [ 29].
The biology of central sensitivity syndrome was concluded to be based on neuroendocrine aberrations, including central sensitization, that interact with psychosocial factors to cause a number of symptoms [ 18].
The concept of central sensitivity syndrome has been suggested to be based on mutual associations among the central sensitivity syndrome conditions as well as the evidence for central sensitization among several central sensitivity syndrome members.
Central sensitization is an emerging biopsychosocial concept currently considered to characterize a wide spectrum of interrelated FSS, which may subsequently be better defined as central sensitivity syndromes [ 18].
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