Sentence examples for sensitization suppression from inspiring English sources

Several mechanisms have been suggested including central sensitization, suppression of descending inhibitory pathways, excessive activity of glial cells, and abnormalities of neurotransmitter release [2].

Order of stimulation sites was counter-balanced to prevent ordering effects and exact stimulation sites were varied to prevent carryover effects due to spatial summation, local sensitization, or suppression of nociceptors.

This is often attributed to Ca2+-sensitization, whereby suppression of myosin light chain phosphatase activity raises contractile force independently of further increases or even decrease in intracellular Ca2+[ 15, 18- 21].

To assess the use of oral glucose tolerance testing (OGTT) to predict efficacy of insulin sensitization (metformin) or suppression (octreotide) because insulin resistance and insulin hypersecretion may impact pharmacotherapeutic efficacy in obese children.

These results are consistent with our re-sensitization screens identifying EGFR whose suppression restores sensitivity to crizotinib in SMARCE1-knockdown cells (Supplementary information, Figure S5).

This represented a 98% reduction in tumour burden and a significant sensitization of TRAIL mediated suppression of metastatic disease.

As 14-3-3ζ 14-3-3ζ 14-3-3ζd is breast cancers with a poverexpressed, and ins elevated expression is associated with activation of growth factor and mitogenic signaling pathways and with endocrine resistance, our data imply that 14-3-3ζ should serve as a marker of resistance and a key therapeutic target for endocrine therapy sensitization and effective tumor suppression.

In parallel to the transcriptome analysis, we performed unbiased shRNA re-sensitization screens to identify kinases whose suppression restore sensitivity to crizotinib in SMARCE1-knockdown cells, using a lentiviral shRNA library representing the full complement of 518 human kinases.

We noticed a partial sensitization to cytarabine on MLH1 suppression.

In contrast to TRAIL, only GSK-3 β suppression led to sensitization of TNFα-induced cell death in PDA, an effect recapitulated in GSK-3 β-null MEFs.

Although Ribavirin sensitization to FLU may involve suppression of AKT signaling, western blot analysis in available samples revealed no significant association between ribavirin sensitization and basal AKT phosphorylation (data not shown).