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Neuronal mechanisms involved in arthritic pain are the peripheral sensitization (sensitization of primary afferent fibres supplying the joint) and central sensitization (sensitization of spinal cord neurons).
Specifically, as reported in other studies with psychostimulant sensitization, sensitization tends to be most robust in animals challenged after a sufficiently lengthy washout period following a repeated induction phase of pre-treatment [ 27, 30, 31, 36, 52, 63, 64].
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When the human body has disease, acupoints on the body surface may be sensitized with various types of sensitization, and acupoint heat-sensitization is a type of acupoint sensitization.
Table 2 Photovoltaic parameters of Sb2Se3 sensitized SnO2 photoanode-based solar cell prepared with different sensitization time Solar cell Sensitization time (min) V oc (V) J sc (mA/cm2) FF C-30 30 0.272 0.715 49 0.31 C-60 C-60 60 0.182 0.795 41.
The titers of DNCB-specific Abs were higher in animals sensitized multiple times with DNCB compared to animals receiving a single DNCB sensitization, and likewise, the severity of dermatitis at the site of DNCB application was always higher in animals with multiple DNCB sensitizations as opposed to single sensitization.
One possibility is that early exposure causes the immune system to produce protective antibodies, but without allergic sensitization.
On the contrary, it indirectly contributes to the initiation of central sensitization; i.e., sensitization of the spinal cord nerves.
Altogether, mediators released in inflamed skin could contribute to peripheral sensitization, especially via TRPV1 sensitization, thus facilitating pain and itching.
Therefore, and not in contrast to peripheral sensitization process, central sensitization may also be involved in the generation of TrP referred pain in children with CTTH.
The developments related to grain boundary engineering of austenitic stainless steels and the beneficial role of a high fraction of low energy grain boundaries against sensitization and sensitization induced stress corrosion cracking is described.
Only using or reporting a few tests, e.g. like in this case pressure pain thresholds, does not give the full picture of the disorder and cannot distinguish between sensitization and no sensitization.
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Justyna Jupowicz-Kozak
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