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It is hypothesized that in individuals with multiple chemical sensitivity (MCS), a sensitization process has occurred that is akin to behavioral sensitization and kindling observed in rodents.
The other makes use of the antenna effect (or sensitization process) [9].
This enabled simplification of the sensitization process and yielded uniform, high-quality photoanodes.
Patients with chronic pain may be more susceptible to develop a central sensitization process [85].
And trigeminovascular system (TGVS) activation participates in the nociceptive transmission, thereby enhancing this chronic sensitization process [8].
XRD patterns indicate that the crystal structure of TiO2 remains unchanged after sensitization process, as reported in similar work [28].
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Nevertheless, pressure pain hypersensitivity within the trigeminal area may reflect both peripheral and central sensitization processes.
In a manner similar to that of TRPV1, TRPA1 activity is controlled by desensitization and sensitization processes.
Interestingly, opioids induce hyperalgesia via many of the same neuro-inflammatory and central sensitization processes that occur with the development of neuropathic pain.
It is possible that similar sensitization processes also occur in children with CTTH, although longitudinal studies are needed to further elucidate the role of active TrPs in children with CTTH.
These results combined gives support for the involvement of peripheral mechanisms in localized chronic myalgia, and may implicate that patients with chronic pain constantly have their immune system switched on with higher levels of inflammatory mediators leading to peripheral sensitization, which may drive central sensitization processes and pain [40].
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