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Central sensitization Increased responsiveness of nociceptive neurons in the central nervous system to their normal or subthreshold afferent input [20].
Peripheral sensitization Increased responsiveness and reduced threshold of nociceptive neurons in the periphery to the stimulation of their receptive fields [32].
Both high force tasks induced median nerve macrophage infiltration, spinal cord sensitization (increased substance P), grip strength declines and forepaw mechanical allodynia by task week 12.
are able to modulate the postsynaptic responses with further transmission to supraspinal sites (thalamus, anterior cingulated cortex, insular cortex, and somatosensory cortex) via the ascending pathways [ 22, 24, 25].The simplest form of plasticity in nervous systems is that repeated noxious stimulation may lead to habituation (decreased response) or sensitization (increased response) [ 26].
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Clearly, CdS sensitization increases the photocatalytic efficiency.
This sensitization increases the risk of vaccine allergic reactions [56].
Our management protocol aimed at decreasing the sensitization, increasing range of motion and functional restoration.
Thus, sensitization increases the ability of organophosphorus pesticides to cause airway hyperreactivity and also changes the mechanism from IL-5 independent to IL-5 dependent.
At low-to-moderate levels, irritant exposure in conjunction with allergen exposure may lower the threshold for sensitization, increase the frequency of sensitization (both induction and elicitation phases), increase the degree of edema and erythema, and enhance the proliferative response of lymph node cells.
Prin Mathieu et al. [ 12] measured ATG immunoglobulin levels pre- and post-first dose of ATG: they found that 8.9% of the patients had pre-dose antibodies, with sensitization increasing rapidly to 71% post-dose, but found no correlation between pre-immunization and occurrence of serum sickness.
Interestingly, from our correlation analysis it emerges that the more pronounced the habituation, the more the CM number of headache days and sensory sensitization increase.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com