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However, even though TNFα induces NF-κB activation, TNFα functions primarily as a sensitizer of TRAIL-induced apoptosis and it seems that TNFα-mediated apoptosis sensitization function apparently overpowers the TNFα-induced and NF-κB-mediated tumor cell survival effects.
Nevertheless, TNFα-mediated apoptosis sensitization function apparently overpowers TNFα-induced and NF-κB-mediated cell survival effect to result in an overall apoptosis sensitive phenotype in human colon carcinoma.
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Together, these data suggest that APPL1 may exert its insulin-sensitization function by promoting IRS1's interaction with IRβ.
Neuroplasticity and subsequent CNS sensitization include altered function of chemical, electrophysiological, and pharmacological systems [ 22, 28, 29].
Youth on metformin or lifestyle modification were included to assess if despite insulin sensitization β-cell function contributes to 2-h glucose determination.
Changes in locomotor function, sensitization to pain and depression/anxiety-like symptoms were found in their high-fat-induced model of OA.
During the study investigating the relationship between A. fumigatus sensitization and lung function in asthma [ 15], we noticed that a significant number of other fungi were being cultured, particularly in those patients who were not sensitized to A. fumigatus.
The noble metal nanoparticles show both electronic and chemical sensitization: the first functioning as an electron sink resulting in a new band structure of the photocatalyst, and the second interacting chemically with the oxygen and argon adsorbed from the environment.
Thus, the LPS instilled together with OVA during the sensitization phase likely functioned to promote the development of these cells, which probably proliferated during the challenge phase.
Community sensitization via open day functions, use of posters and use of influential people such as chiefs were suggested in this study as promoting factors.
The optical, morphological properties and photovoltaic characteristics of SnO2/Sb2Se3 photoanodes were analysed as a function of sensitization time.
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