Your English writing platform
Discover LudwigExact(2)
In the second part of the study, we examined if sensitization develops to cocaine-induced antinociception and its ability to increase the antinociceptive effect of morphine.
In general, eczema peaks in the child's first years of life as an "entry point" for subsequent allergic disease, and consequently the prevalence of asthma and allergic rhinitis increases over time as sensitization develops [ 8].
Similar(58)
This may explain the process of peripheral sensitization developed during the attack of migraine.
Sensitization developed to the motor stimulatory effect of cocaine in both groups, regardless of morphine treatment on the prior day.
Mechanisms of nociceptive sensitization developing at the synapses between primary afferent fibers and secondary order neurons of the caudal trigeminal nucleus, and in upper regions of the pain neuraxis likely contribute to the development of the typical unilateral attacks of pain associated with CH.
The ONB is thought to interfere with the subsequent sensitization developing during the event of acute headache attacks, modulating the excitability of second-order neurons receiving input from both trigeminal and cervical afferents upon stimulation of either afferent input [15, 16].
Surprisingly, these prior studies demonstrated that despite the elimination of NMDAR-dependent LTP in DA neurons in these NR1 knockout (KO) mice, cocaine sensitization developed normally [10], [11], suggesting that locomotor sensitization does not require NMDAR-dependent neuronal plasticity.
This might be caused by sensitization developed through other allergic conditions [ 8].
The hyperalgesia of central sensitization usually develops as part of ongoing pathology (i.e., damage to peripheral or central nerve fibers, cancer, rheumatoid arthritis) and is considered maladaptive.
Treating an attack early widens responsiveness to triptans in allodynic patients by preventing central sensitization from developing [17].
Sensitization also developed to the antinociceptive effect of cocaine 24 h but not 1 wk after the last cocaine injection.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com