Sentence examples for sensitization contributes from inspiring English sources

Although in most patients allergen sensitization contributes to asthma, attempts to intervene using allergen-reduction strategies [ 13] or allergen-specific immunotherapy [ 14] have proved disappointing, despite its proven efficacy in allergic rhinitis [ 15].

In adults, there is good evidence that central sensitization contributes to many prolonged chronic pain states (Woolf, 2011), although in some cases, such as fibromyalgia (Staud et al., 2009), the pain requires a continuous peripheral input.

Both NMDA and non-NMDA receptors involved in central sensitization contribute to the development of BV-induced mirror-thermal hyperalgesia [ 51].

Both peripheral sensitization and the classical or modern forms of central sensitization contribute to hyperalgesia (increased responsiveness to noxious stimuli) although their mechanisms and loci in the pain pathway may vary.

Triglyceride-lowering and HDL-C raising effects of bezafibrate lead to decreased systemic availability of fatty acids, diminisHDL-C raisingd uptakeffectsscle with improfement of insulin sensitization, contribezafibrate to a reduction of pleada glucose levels [ 40, 42].

In addition to the Ca2+ influx via both populations of L-type Ca2+ channels, a time-dependent Ca2+ sensitization contributed to the depolarization-induced contractions of the mouse aorta.

After application of an intense and prolonged injury, ongoing excitation of primary nociceptive neurons leads to neuronal changes both in the primary afferents (peripheral sensitization) and in the spinal dorsal horn neurons (central sensitization), contributing to the development of chronic pain [ 3].

Our hypothesis is that changes in synaptic plasticity at various loci of mesolimbic circuits during cocaine exposure contribute to the formation of drug-associated memory, and elevated BDNF expression after cocaine withdrawal results in further synaptic sensitization that contributes to cue-induced drug craving and drug-seeking behavior.

Anxiety disorders may play an important role in peripheral and central mechanisms of pain sensitization which contributes to the evolution to chronic headaches [18, 19].

The observation that CCI-779 was quite ineffective on neuronal responses in the absence of nerve injury [ 57] allows to confirm that mTOR signaling at the spinal level is an integral element of nociception and that its role in central sensitization likely contributes to the persistence of pain.

Schwedt and colleagues suggest that central sensitization may contribute to the persistence of any such new headache following EVT [8].