Sentence examples for sensitization approach from inspiring English sources

Using primary-sequence alignments to guide our enzyme engineering, we have successfully introduced allosteric-inhibition sites in four classical PTPs PTP1B, PTPH-1, FAP-1, and HePTP from four different PTP subfamilies, suggesting that our sensitization approach can likely be applied widely across the classical PTP family to generate biarsenical-responsive PTPs.

To this end, we could show that a sensitization approach with the commonly used anticancer compound 5-fluorouracil (5-FU) in conjunction with systemically administered MSC.sTRAIL worked in vitro and in vivo.

Therefore, to also test utility of TRAIL-R1-specific variants in conjunction with an alternative sensitization approach to 5-FU, namely XIAP inhibition, we generated stable XIAP knockdown clones of the TRAIL-resistant pancreatic PancTu1 cancer cell line.

In a second sensitization approach, we targeted the antiapoptotic protein XIAP (X-linked inhibitor of apoptosis protein) by RNA interference (RNAi) in TRAIL-resistant pancreatic carcinoma cells and could show that MSC.sTRAILDR4 exerted significantly increased apoptosis-inducing activity as compared with MSC.sTRAIL or MSC.sTRAILDR5.

What would be some of the ways to sensitize men, like Onyango, about the benefits and risks of male circumcision?" Several sensitization approaches were discussed by participants.

Therefore, a co-sensitization approach has been used for achieving enhanced performances in DSSCs wherein N719 was co-sensitized with PTZ-2 and PTZ-3, respectively.

Tyrosine and serine/threonine kinases are equally amenable to the drug-sensitization approach, which has been used to generate selective inhibitors of mutant Src-family kinases, Abl-family kinases, cyclin-dependent kinases, mitogen-activated kinases, p21-activated kinases and Ca2+/calmodulin-dependent kinases.

With implementation of the dermal sensitization QRA approach for fragrance ingredients, IFRA/RIFM are recommending use of the RIFM standard human repeated insult patch test (HRIPT) protocol for generation of confirmatory human data for the induction of dermal sensitization in a normal human population.

The coexistence of severe asthma refractory to the conventional pharmacological approach and sensitization to at least one perennial allergen represent the current indications for omalizumab prescription.

Such progress provides us now with new opportunities to consider alternative approaches to sensitization testing, including the design of in vitro test methods.

Proactive approaches like sensitization, continuing education and outreach to researchers and other stakeholders in research could yield better outcomes than strict punitive treatment and humiliation.