Interestingly, a SNP upstream of TACR1 present in alcohol-preferring rats increased transcription factor binding, gene transcription, alcohol self-administration and sensitivity to the NK1R antagonist L822429 [Schank et al., 2013].
On the other hand, in a report by Robledo et al [ 18], the heightened operant response induced by the cannabinoid antagonist SR in MDMA self-administration indicated a decrease in sensitivity to the motivation for obtaining the drug.
and sensitivity to the office.
There is also heightened sensitivity in the administration to being perceived as anti-Islamic at a time when there is talk of a war against Iraq and increased violence in the Middle East.
In the studies presented here, the hypothalamus appears to play a key role in mediating the effects on hepatic insulin sensitivity in response to the administration of both central and peripheral HN and its analogs.
We expect the sensitivity of the administration claims data to be generally lower than that of medical records data.
Variations in the actual costs of SIAs likely to reflect the extents to which economies of scale associated with campaign-based delivery can be attained, the underlying strength of the immunization program, sensitivities to the relative ease of vaccine administration (i.e. orally, or by injection), and differences in disease-specific programmatic approaches.
In addition, EGF-Tg mice exhibited higher sensitivity to repeated cocaine administration in a locomotor test.
Within a discrete subregion of the NTS, the rostral portion, very few tdTOM-IR or GFP-IR neurons colabeled with pSTAT3-IR (Fig. 1; bregma −6.84 mm, tdTOM-IR 6.3 ± 2.6% and GFP-IR 4.1 ± 2.9%; bregma −7.20 mm, tdTOM-IR 10.0 ± 1.4% and GFP-IR 25.0 ± 6.0%), highlighting a localized site of potential ectopic reporter expression or LepRb neurons of lower sensitivity to exogenous leptin administration.
The White House's plans have been thwarted by Chinese objections, by security issues and by sensitivities that the administration chose not to upset, even as Mr. Bush faced criticism from human-rights campaigners and lawmakers here in Washington for not doing and saying more.
Far from being broken, it could be argued, American democracy is working with exquisite sensitivity, allowing the administration to advance where it has the people's support but checking it when it overreaches.Needless to say, the people are not always well-informed, let alone right or consistent in their wants.
