Sentence examples for sensitivity to suppression from inspiring English sources

These cell lines exhibited varying degrees of sensitivity to suppression of CTNNB1, with the β-catenin-negative line, SKBR3, being the least sensitive (Fig. 3C).

Fasting plasma glucose concentration depends entirely on the fasting rate of hepatic glucose production and, hence, on its sensitivity to suppression by insulin.

In this regard, it has been recently reported that CD4+CD25- cells from MRL/Mp mice show a reduced sensitivity to suppression by autologous Treg lymphocytes.

In insulin-treated type 2 diabetes, insulin dose correlates with the extent of fatty liver (35), and in turn, this is associated with insulin sensitivity to suppression of hepatic glucose production (36).

Interestingly, the APC-mutated DU4475 cells, while exhibiting evidence of β-catenin activation and sensitivity to CTNNB1 suppression, were relatively unaffected by CSNK1E suppression (Fig. 3D, E), suggesting that CSNK1E may function upstream of APC in Wnt/β-catenin signaling.

NK cell activity displays differential sensitivity to adrenergic suppression in male and female rats, and this increases the susceptibility of male rats to experimental lung metastases.

In this case, the effects of sex appeared to be mediated by the inhibitory effects of estrogen on IL-6 signaling rather than testosterone dependent sensitivity to immune suppression.

Moreover, cells transformed by CSNK1E demonstrated an enhanced sensitivity to β-catenin suppression compared to control cells, suggesting that the CSNK1E-transformed cells develop a dependence on β-catenin function for proliferation (Fig. 6C).

Given the reciprocal relationship between Treg cells and the key pro-inflammatory cytokine, IL-17 [23], we explored if reduced IL-17 production by effector cells from HIV+ subjects could be one mechanism for their increased sensitivity to Treg-mediated suppression.

This disparity in response demonstrates a species-specific sensitivity to phthalate-induced suppression of fetal Leydig cell steroidogenesis.

The disparity in response suggests a species-specific sensitivity to phthalate-induced suppression of androgen biosynthesis, and invites speculation as to the human response.