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Previous work has demonstrated that the ETR1 homodimer is linked by disulfide bonds based on its sensitivity to reducing agents such at dithiothreitol (DTT) (Figure 3A) [13A.
It appears that CTLD1 is essential for stabilizing the structure of this epitope given the presence of a disulfide bond between CTLD1 and FnII which explains, at least in part, the sensitivity to reducing conditions.
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Among the current options, the DDA (Digital Detector Array) is considered as one of the best solutions to replace industrial films, as well as to increase the sensitivity to reduce the inspection cycle time.
We cannot rule out, however, the possibility that inherited maternally derived protein remaining at this stage is sufficient to support ciliogenesis, with centriole duplication in dividing cells showing a greater sensitivity to reduced Poc1 levels.
Three variants, (L181A, I286A, and L293V) exhibited sensitivity to reduced pyridoxine levels relative to the major allele, but no heightened sensitivity to reduced heme levels based upon growth-rate measurements.
Of note, when implementing a urinary test to stratify the need for cystoscopy, it is sensitivity (to reduce false negative tests) that is more important than specificity.
Additionally, the Δ hicB strain had increased sensitivity to ciprofloxacin, reducing the MIC by half.
A minimum number of random variables were chosen from a sensitivity analysis to reduce the computational cost.
Hair digestion and analytical methods using LC-MS/MS were developed in house to increase sensitivity and to reduce the amount of hair required [38].
All attempts to improve its sensitivity and to reduce the background failed.
Waveform optimization has proven to be an important tool for maximizing analyte sensitivity and to reduce fouling at the electrode.
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