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For the classical Wicke Kallenbach cell and binary mixtures, it was found that there are narrow intervals of outlet mole fractions in which the related boundary-value problem exhibits the maximum sensitivity to modifications of the transport parameters, i.e. there are the optimal conditions for regression analysis.
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Knowledge of these scales, their validity, their sensitivity to modification, and their specificity and interpretation pitfalls is a prerequisite to good evaluation in daily practice and clinical research.
Greater sensitivity to modification (Mitas 1997) and initial nuclear magnetic resonance (NMR) data (Zheng et al. 1996) suggested that the adenine bases in CAG repeat hairpins might be extrahelical.
In this study, the novel sensitivity reanalysis methods are suggested to obtain the static displacement sensitivity to local modifications efficiently.
Building on its multiscale and mechanistically enhanced sensitivity to landscape modifications, we applied this calibrated tool to a theoretical landscape planning problem.
This indicates that Skp1 is conformationally flexible in its complexes with FBPs, which is consistent with the proposed conformational sensitivity to Pro143 modifications.
By contrast, the adducted to unadducted peak ratio corresponding to Lys-132 adduction was 0.23, indicating a relatively lower sensitivity to HNE modification.
With the ultimate goal of identifying and targeting safe sites in the genome at which to insert corrective genes, we previously explored three active mammalian transposases, piggyBac, Tol2 and SB11 (a hyperactive Sleeping Beauty) for their sensitivity to molecular modification [ 15].
Given the complexity of in vivo oxidative stress and variability in the intrinsic ROS resistance of different proteins, it is not surprising that some proteins may show differential levels of sensitivity to oxidative modification at middle age.
Finally, it has been found that there is a strong sensitivity to very small modifications of some system parameters.
Sensitivity to covalent nucleotide modifications has also been developed into an assay for detecting modified cellular RNA [39].
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