(2013), that models trained on the NCI60 data set are likely to fail on sensitivity data measured with a different experimental procedure, e.g. the CCLE or GDSC datasets.
These data suggest that individuals with less sensitivity to insulin may fail to shift brain networks away from reward and toward cognitive control following a meal.
Likewise, stratifying the AR cohort and controls by the presence of sensitivity to different allergens failed to detect any evidence of association between the genotyped SNP markers and AR (Table S1).
In addition, the lumped parameter model is developed to calibrate the estimated error by compensating the thermal response time induced by the tissue temperature change that the current infrared thermal imaging system with limited thermal sensitivity may fail to capture.
In summary, we have shown how sequencing technologies with inferior sensitivity may fail to detect clinically relevant oncogene mutations in cancer patients.
Although these expectations can explain the observed proportion of F2s with low sensitivity, they fail to explain the proportion with high sensitivity (60.2%; χ test, P < 10−9).
A proxy with a low sensitivity may fail to detect the effectiveness of asthma treatment that works for mild but not for severe asthma cases.
For an epidemic-prone disease such as cholera, a surveillance system with low sensitivity could fail to detect small outbreaks, and potentially delay mobilization of life-saving clinical resources such as IV fluids and preventive measures.
Whilst in many applications the EQ-5D has been shown to be a valid and reliable measure of patient health, it has also been argued that in some contexts the three-level version of the EQ-5D may lack sensitivity or fail to capture important aspects of health in certain disease areas.
The fact that we did not find any significant difference between ANA staining patterns in patients fulfilling the ACR-82 classification criteria and those that only met Fries' criteria probably reflects that the ACR-82 criteria have a lower sensitivity and fail to identify all patients with 'clinical SLE' and at least two typical organ manifestations.
While these receptors are helpful in identifying groups of tumours with differing sensitivity to endocrine therapy, they fail to predict accurately in individual cases.
