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Having found previously that leukemic cells with multidrug resistant (MDR) phenotype, but not their sensitive counterparts, exhibit collateral sensitivity to cold stress in a P-gp-dependent manner, our aim was to study the signaling pathways involved in this phenomenon in sensitive (L1210) and resistant cells (L1210R and CBMC-6).
The progeny segregated in their sensitivity to cold storage and the sensitive peaches developed 80% woolliness and the tolerant peaches had no woolliness during ripening after 1 week's storage at 5°C [ 15, 16].
The different chemotypes have differential sensitivity to cold, with the phenolic chemotypes more freezing sensitive and the nonphenolic chemotypes more freezing tolerant.
Anon Dry skin can be a sign of an under-functioning thyroid, other symptoms of which include sensitivity to cold, fatigue, weight gain and low mood.
Like anorexic women, anorexic men can exhibit all the physiological signs of starvation, including cardiac irregularities, severe dehydration, thinning hair, bruising skin, osteoporosis and sensitivity to cold.
In addition, nonfeathered skin areas, such as the legs and feet, have little sensitivity to cold or warm stimuli.
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This appears to reflect both relatively low sensitivities to heat and relatively high sensitivities to cold effects in these locations.
Only the tooth 47 showed percussion sensitivity and was not sensitive to cold.
And increased sensitivity to the cold does not pose a big health risk, or require any specialized medical treatment.
The aim of the present study was to examine the contribution of handedness and gender to sensitivity to tonic cold pain in healthy subjects.
Dr. Sharon A. Brangman, a professor of medicine at SUNY Upstate Medical University and a past president of the American Geriatrics Society, said increasing sensitivity to the cold could be a sign of a medical problem like hypertension or diabetes (though for some diabetics, the real danger is decreased sensitivity in their extremities that may leave them unaware of injury).
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CEO of Professional Science Editing for Scientists @ prosciediting.com