Sentence examples for sensitivity to apoptosis from inspiring English sources

E1A-induced cellular sensitivity to apoptosis inducing injuries of various types (immunological, chemical, and physical) has been well described5.

However, p53 also has essential roles in these cells through DNA damage repair for maintaining genomic integrity and high sensitivity to apoptosis for eliminating severely damaged cells.

Selective knockdown of Myc levels in these cells by RNA interference increased sensitivity to apoptosis with compound treatment.

The maintained or elevated expression of these genes in human iPSC and ESC (Figure 2) likely contributes to high sensitivity to apoptosis for eliminating damaged cells16 and maintenance of genomic stability44 in these human pluripotent stem cells.

Conversely, activation of caspase-3 often increases cancer cell sensitivity to apoptosis (Devarajan et al., 2002; Guicciardi and Gores, 2013).

When Harrison et al. stimulated extrinsic and intrinsic apoptotic pathways in the normal and culture adapted cells, it was the adapted cells that showed higher sensitivity to apoptosis (Harrison et al., 2009).

In variance, CD25− T cells display balanced sensitivity to apoptosis under both conditions.

The cell cycle status might affect the sensitivity to apoptosis [29].

Furthermore, silencing NPHP1 per se resulted in increased sensitivity to apoptosis in parental MDCK cells (Figure 5C).

We hypothesized that expression of these cell cycle genes in DP thymocytes might contribute to their inherent sensitivity to apoptosis.

The immature pro-B cells from LEF-1 deficient mice display increased sensitivity to apoptosis [29], although the exact mechanism is unclear.