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In the same way we may gradually lose our sensitivity to a specific perfume, we seem to become desensitized to negative emotions associated with telling a lie, the research team found.
CTL can show exquisite sensitivity to a specific peptide/HLA ligand, with as few as 3 target peptide/MHC complexes being sufficient for CTL-specific cell lysis in vitro[38].
However, coexpression is likely to diminish photoreceptor sensitivity to a specific wavelength if total opsin expression in that cell is constant.
Individual response to ADHD therapy is influenced by a number of factors, including severity of the disorder, sensitivity to a specific treatment, vulnerability to treatment-related adverse effects, and personal values and preferences regarding treatment outcome [ 46].
However, demonstration of the contribution of the HER2/neu protein expression and c-erbB-2 gene amplification to the sensitivity to a specific targeted agent such as T-DM1 requires functional validation.
Third, it will also be interesting to test whether the E2F4 signature can predict sensitivity to a specific drug or treatment, for example the CDK inhibitors, which can repress the E2F4 regulatory program.
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Thus, even though it does not seem to predict a specific sensitivity to a particular class of drug, it may indicate a subset of BC patients in which adding taxanes to anthracylines may be of interest in spite of the absence of lymph node invasion.
These include an increased sensitivity to staurosporine, a specific Pkc1p inhibitor, and susceptibility to cell-wall perturbing treatments such as hypotonic- and heat shock conditions and zymolase treatment.
A skillfully navigated, personalized discussion between an interested mother and pediatrician, employing sensitivity to a mother's specific technical understanding and personal concerns on this topic, is likely the best option, although perhaps the most difficult one.
Third, an algorithm considers all possible combinations of lower (L) and upper (U) levels, subject to a constraint on U that forces the total sensitivity to equal a specific percentage (e.g. 35%) of the acquired breathing signals.
In their current form, electronic devices probably lack the sensitivity to distinguish a specific cancer from other cancers, which is a crucial requirement for practical use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com