To test the variation in sensitivity of timeliness of outbreak detection, we analysed the predictions of all 102 definition combinations against outbreaks in an interior state (Matto Grosso do Sul, A6, 2010), an urban south eastern state (Rio de Janeiro, B8, 2011) and a northern state (Maranhão, C4, 2007) all with differing DENV transmission dynamics (Fig. 5).
A major public health preparedness challenge is increasing the sensitivity and timeliness of recognition of individual, potentially sentinel cases of category A bioterrorism agent disease.
Finally, we assessed, over a range of specificity, the sensitivity and timeliness of syndromic surveillance and the detection benefit of syndromic surveillance compared with clinical case finding for each simulated outbreak.
Most studies compared drug sales data to reference surveillance data using correlation measurements or indicators of outbreak detection performance (sensitivity, specificity, timeliness of the detection).
What is the best approach to identify the BRCA1 mutation carriers among young women with newly diagnosed breast cancer, in terms of timeliness, sensitivity, specificity?
New threats of bioterrorism have resulted in increased pressures to improve the sensitivity and timeliness of routine disease surveillance, particularly through the use of improved electronic data interchange.
Formal statistical comparisons of sensitivity, timeliness, adjusted timeliness, AUC and weighted AUC for the EARS and negative binomial cusums were performed using Friedman Rank Sum Tests as implemented in the Stats package for the R software version 2.6.0 [ 21].
This procedure was performed on all significant signals using the above criteria Here we examine the detection sensitivity and timeliness of the method using the two levels of geographical resolution (i.e. census tract centroids and individual addresses) applied to the confirmed outbreaks of the p9 cluster (Table 1 and Figure 3).
More specifically, we used the dates of these confirmed p9 outbreaks to assess both the sensitivity and timeliness of the detection algorithm presented here when using census tract centroids versus individual addresses.
We investigated the effect of varying the spatial resolution in a variant of a widely used space-time detection technique on the sensitivity and timeliness of identifying both simulated and confirmed TB outbreaks, and examined the dependency of these performance measures on the amount of historical data required.
The present study has evaluated the specificity, sensitivity, and timeliness of detection using a training set containing six years of data.
