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As expected, donor CD4+ and CD8+ T cells had reduced IL-7Rα expression when transferred into Rag2KO but not untreated naive recipients (Fig. 3A), validating the IL-7 detection sensitivity of the methodology.
The purpose of this study was twofold: to develop a methodology for the estimation of land surface temperature for non-urban areas and to analyze the sensitivity of the methodology.
Moreover, in order to investigate the sensitivity of the methodology to different crowding conditions, the proposed approach was applied in relation to three different levels of travel demand obtained by means of the first type of surveys, whose results, expressed in terms of a distribution function, are shown in Fig. 4.
This difference might be related to the higher sensitivity of the methodology applied nowadays.
We used this information to estimate sensitivity of the methodology.
Hence, false negatives are also possible given the sensitivity of the methodology [ 14].
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The difference in these results can be explained by the difference of bacterial detection sensitivity of the methodologies as well as amplification or cloning bias.
In order to improve the sensitivity of the methodologies used to dissect the genetic networks underlying dilated cardiomyopathy, we built a dual-regime OCT instrument dedicated for the in situ measurement of multiple cardiac parameters in the Drosophila larval heart.
This discrepancy highlights the difference in sensitivity of the methodologies used, e.g. microarray analysis (this study) vs. quantitative RT-PCR analysis [ 47].
Other studies, using autoradiographic techniques with selective ligands, failed to detect the mu and delta opioid receptors in rat CP brain [ 25, 26], probably due to the lower sensitivity of the methodologies used.
The observation of the internal standards (200 fmol) in this DNA sample (500 μg or 1.4 μmoles of bases) gives us a measure of the upper limit of the sensitivity of this methodology of ≤1.4 adducts per 10 nucleosides.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com