Therefore, we consider it more likely that smoking reduces FGF23 sensitivity, thus necessitating an increased production to maintain phosphate excretion.
Progressive decline in β-cell function along with decreasing insulin sensitivity generally necessitate the addition of other OADs, and eventually, insulin therapy is required in order to achieve adequate glucose control [ 2, 3].
It seems that improving BARD's diagnostic sensitivity would necessitate incorporation of the markers of subclinical portal hypertension (e.g., platelet count) and hepatic synthetic capacity (e.g., albumin).
Situations like these necessitate sensitivity to ethnicity, race, religious affiliation, linguistic challenges, single parenthood, and familial characteristics.
Western scrub-jays face two key ecological challenges that necessitate sensitivity to delays between caching and recovery.
Cache-theft and cache-degradation are time-dependent processes in scrub-jay ecology that might necessitate sensitivity to delays between caching and retrieval.
When dealing with crystals of large molecules, solvent loss or sensitivity to air/moisture may necessitate rapid handling and low temperatures, which have additional potential to increase the probability that groups become disordered.
A major drawback of the NCA, and other methods carried out under neutral conditions, is the lack of sensitivity of these assays, necessitating the measurement of DSBs after exposure of cells to high radiation doses (>10 Gy) that will essentially kill all the cells.
Either case necessitates increased detection sensitivity to achieve similar signal-to-noise or contrast-to-noise ratios as in motion-free static images.
Unfortunately, these criteria have low sensitivity, lack prognostic value, and necessitate an invasive procedure.
