Moreover, the Jel1 tderivatives dexpressing expressing MRE11, mre11-H59A, mre11-H125N or mre11-H213Y exhibited CPT-sensitivity essentially indistinguishable from the corresponding Jel1 mre11Δ derivatives (Fig. 3, compare lower and upper).
When this data was normalized, we found that wild-type and ecr2-1 seedlings had indistinguishable sensitivity to ethylene.
Those caveats emptor notwithstanding, that blood insulin content is increased by CR in GHR-KO mice dovetails with the improved performance in glucose bolus assimilation, decreased insulin sensitivity, and (statistically indistinguishable) decreased gluconeogenic capability of GHR-KO mice on CR relative to their A.L. counterparts.
Both immature (IgM+ IgD− CD23−) bone marrow B cells [ 12] and mature (IgM+ IgD+) splenic B cells [ 13] are susceptible to tolerance induction and display indistinguishable sensitivity to the tolerogenic signals of different avidity provided by a range of concentrations of soluble HEL (sHEL) [ 13, 14].
You might take the example of Hunter S Thompson who, for all his wit, sensitivity and imagination, was indistinguishable in his darker moods from the kind of violent, unforgiving monster whose voice resonates from some of his pages.
Interestingly, the relatively rapid kinetics of EGFR-GRB2 binding, which may not prevail for all EGFR adaptors, produces EGFR-GRB2 complex sensitivity results that are indistinguishable from those for phosphorylated receptor (Supplementary Figure S2a d).
Likewise, values for contrast sensitivity and temporal resolution were indistinguishable between WT and rl−/− mice (Table 1; Fig. 4b, c).
These results suggest that the Mn2+ and inhibitor sensitivity of the recombinant MLCP is indistinguishable from that of the native MLCP enzyme.
Heat-shock-induced AMPK impairment in adult stages produced a significant reduction in starvation survival (Figure 2E-F), and starvation sensitivity in animals bearing AMPK transgenes were indistinguishable from wild-type animals under uninduced experimental conditions.
Indeed, double heterozygous combinations (+/keyc02831; +/relE20 and ird5F22/relE20) displayed increased sensitivity to CrPV infection while single heterozygous controls were indistinguishable from background w1118 flies (Figure 4H I), except for heterozygous ir5F22/+ flies which developed resistance to CrPV infection (Figure 4I).
