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The increased sensitivity gained derives mainly from very effective antigen sequestration and the amplification process that occurs as a result of the large number of barcode DNA strands released for each antigen recognition and binding event.
This paper describes the decisions behind the design principles used and how the logarithmic progression of sizes led to the development of the logMAR designation of visual acuity and the improved sensitivity gained from letter-by-letter scoring.
The sensitivity gained by additional POM2 epitopes is also apparent in the amount of PrP captured by POM2 immunoprecipitation (Fig. 3C).
Despite the increased sensitivity gained by optimizing the concentrations of all 3 antibodies, the improved signal was still quite low when compared to previously reported values [ 23].
However, in the current study, a general sensitivity gained during the process of domestication does not account for differences in performance of independent and cooperative working dogs.
The ability of type I interferons to modulate steroid sensitivity gained further support from studies performed in steroid resistant asthmatics where treatment with IFN-α dramatically improved symptoms allowing their steroid dose to be tapered [ 19].
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The expected sensitivity gains were not fully realized, and a number of different reasons for this are proposed.
Additional improvements of the experiment are aimed at a sensitivity gain of more than one order of magnitude.
Besides its ultrafast time-resolution, a so far largely underappreciated potential of 2D-IR spectroscopy lies in its sensitivity gain.
Moreover, the sensitivity (gain) of frequency detection module and that of amplitude detection module are orthogonally adjusted.
Controllability indexes such as disturbance sensitivity gains, the H∞ norm, and the ISE were considered to obtain optimum disturbance rejection.
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CEO of Professional Science Editing for Scientists @ prosciediting.com