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The specific proportion of any given lineage among primary human tumor samples scoring positive for the presence of the 13-gene signature was found to be very similar to the lineage proportions of signature positive, sensitive cell lines in the CCLE, as probed by the NVP-CFC218 chemical sensitivity experiment described above.
Therefore, a second sensitivity experiment is performed with doubled observed cloud fraction and liquid water path.
In the model sensitivity experiment, however, the positive SST offset is prescribed only over the western Indian Ocean region, where the long-term warming trend is observed in the SST records during 1901 2012.
In the sensitivity experiment, positive SST anomalies similar to those in the observations were added to the western Indian Ocean region (Supplementary Fig. 3). Figure 5b shows the model response in the summer monsoon Hadley circulation, and features a weakening of the local Hadley cell, much similar to the observed trends.
To examine the role of a warming Indian Ocean, a sensitivity experiment (CFSv2WIO) using ensembles (20 members) of short integrations for the summer monsoon season during June September were performed by adding temperature anomalies to the SSTs passed over the western Indian Ocean, to the atmosphere.
Using a coupled atmosphere-ocean general circulation model, we study a 100-year sensitivity experiment in which the global-mean salinity is approximately doubled from its present observed value, by adding 35 psu everywhere in the ocean.
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Key results of sensitivity experiments.
Here, two sensitivity experiments are performed that alter the BC loadings and BC/OC ratios.
M.K.R. and K.R. performed the model sensitivity experiments and the analysis.
Sensitivity experiments are performed to estimate GPP uncertainties due to cloud and aerosol properties.
Here, we perform 20 sensitivity experiments with cloud scaling factors from 0 to 10 without aerosol radiative effects (Methods).
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