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The QIAensemble™ system consists of an analytical subsystem (JE2000™) that utilizes a re-engineered Hybrid Capture® chemistry (NextGen) to maintain the high level of clinical sensitivity established by the digene High-Risk HPV DNA Test® (HC2), while creating improved analytical specificity as shown both in plasmid-based analyses and in processing of clinical specimens.
Areas under the receiver operating characteristic (AUROC) curve were calculated and points for best specificity and sensitivity established, positive predictive value (PPV), negative predictive value (NPV) and accuracy were calculated.
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As precise knowledge of the diagnostic sensitivity is not required for the assessment of such relative changes, the specificity and adjusted sensitivity figures established here should also be usable for similar studies in other regions of the world.
A novel in-situ aging evaluation method with high sensitivity was established.
Model sensitivity is established not only from a weld residual stress perspective, but also from an assessment of the post-weld plastic strain accumulated in the weldment.
This study emphasizes the implementation and exploitation of TD fields using the standard displacement-based FEM, a straightforward exploitation of the relevant sensitivity formulation established here.
Finally, the results of a sensitivity analysis established that the maximum speed, dwell time, and headway are positively correlated with the objective.
Based on these data, thresholds for curvature sensitivity were established.
In vitro sensitivity was established in a recovery experiment by preparing serial colorectal cancer cell dilutions.
A series of sensitivity analyses established that other potential confounders, including age, geography, and viral subtypes, did not obscure or compromise our analytical approaches.
It is tempting to speculate that the heterogeneity of Wnt activity in tumor cells would also influence the sensitivity of established tumors to DNA-damaging agents.
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CEO of Professional Science Editing for Scientists @ prosciediting.com