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FNS patients with multiple movement and sensitivity disorders reported more negative LE than patients with either a movement or a sensitivity disorder.
15 patients met criteria of dissociative motor disorder/dissociative movement disorder (ICD-code F44.4) or dissociative anaesthesia and sensory loss/dissociative sensitivity disorder (ICD-code F44.6), while 30 patients met the criteria of multiple dissociative movement and sensitivity disorders (ICD-code F44.7).
FNS severity (per SDQ-20 score) varied with emotional stress (r = 0.41, p < 0.001) and general traumata (r = 0.39, p < 0.001), while patients with multiple movement and sensitivity disorders reported more childhood sexual abuse than patients with either a movement or a sensitivity disorder (Table 2).
FNS patients reported higher psychological strain (SCL90R-GSI) than HC (t 88) = 8.56, p < 0.001), and patients with multiple movement and sensitivity disorders reported higher psychological strain than patients with either movement or sensitivity disorder (U = 121, z = −2.5, p < 0.05).
FNS diagnoses were confirmed by prominent somatoform dissociative symptoms: SDQ-20 scores significantly distinguished FNS and HC, and within the FNS sample, SDQ-20 scores distinguished patients with multiple dissociative movement and sensitivity disorders from patients with either single movement or sensitivity disorder (see Table 2).
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What is more, the proteolytic activity of pepsin in the larynx may result in sensitivity disorders such as glottic closure reflex and cough reflex.
FNS patients received more comorbid PTSD diagnoses (24%%) than HC (χ (1) = 12.84, p < 0.001), and FNS patients with multiple dissociative movement and sensitivity disorders were more frequently diagnosed with comorbid PTSD (33%%) than patients with either movement or sensitivity disorders (7 %, χ (1) = 3.85, p = 0.05).
González et al. have studied vaspin gene expression regulation in WAT of mice under different physiological (diet, pregnancy, age, and gender) and pathological (gonadectomy, thyroid dysfunction, and growth hormone deficiency) conditions, associated with energy homeostasis and insulin sensitivity disorders.
X.P., as the disease is known, is the rarest and most severe form of light-sensitivity disorder, affecting only one in a million people.
Thomas Ruenger, a dermatologist at Boston University who specializes in light-sensitivity disorders, told me that he found it "very, very hard to believe" that such a display could cause discomfort to even the most acutely light-sensitive person, because the energy level would be "so low" by the time the light reached the skin.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com