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These findings indicate that unpaired or weakly hydrogen-bonded regions, sensitive to the single strand-specific nuclease, occur or can be induced in superhelical DNA.
Dopamine appears to be electrochemically active and reveals interesting adsorption phenomena at low potentials (0.15 0.25 V vs RHE), sensitive to the single crystal orientation.
The front-end is designed to be sensitive to the single photo-electron to detect the weak primary scintillation light produced in the chamber, and also to be able to cope with the electroluminescence signal (several hundred times higher and with a duration of microseconds).
For example, as shown in Fig. 10(a), the value of 〈 σ e e (1 ) σ e e (3 ) 〉 is no longer sensitive to the single excitation resonances, but still exhibits the ring-exchange splitting at ω d ≈ ε + Ω and ω d ≈ ε + Ω + J.
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A major challenge in neuronal stem cell biology lies in characterization of lineage-specific reprogrammed human neuronal cells, a process that necessitates the use of an assay sensitive to the single-cell level.
These oligo Y regions, and their complementary R tracts, were found to be sensitive to the single-strand specific nuclease P1 when under normal cellular superhelical stress.
In particular, Feng and coworkers[20, 21] have proposed that the TUCFs are very sensitive to the motion of single or a few mobile defects.
Although conventional Raman spectroscopy is not particularly sensitive to the detection of single compounds in an acoustically levitated drop below concentrations of approximately 1%, the SERS technique overcomes this limitation and the potential of RALS as a tool to investigate processes that change the molecular state and environment of the target compound is beginning to emerge.
To reduce noise on each PC from insignificantly contributing variables, we "desensitized" each PC by setting to zero any loading whose sign was sensitive to the removal of single patients within the data set whose 95% confidence interval across leave-one-out (LOO) cross-validation spanned zero (29).
The small size and high resistance of C. elegans neurons makes them sensitive to the random opening of single ion channels, probably rendering codes that are based on classical, all-or-none action potentials unworkable.
The binding of human IgG1 to human Fc gamma receptors (hFcγRs) is highly sensitive to the presence of a single N-linked glycosylation site at asparagine 297 of the Fc, with deglycosylation resulting in a complete loss of hFcγR binding.
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