Sentence examples for sensitive to the earliest from inspiring English sources

The authors describe the construction of a multiscale informant rating checklist (Cognitive Change Checklist; 3CL) designed to be sensitive to the earliest stages of cognitive decline associated with degenerative dementias.

Identifying the endpoint most sensitive to the earliest cognitive changes is another challenge.

Thus, fLCI uses nuclear morphology as a biomarker of disease, making it sensitive to the earliest stages of precancerous development.

As a consequence, laminated composites are not so sensitive to the early cracking, and exhibit a good strength-ductility combination.

On the other hand, the annealing-induced increase in Young's modulus, being more sensitive to the early stages of recovery, seems to be smaller with SiO2 than with Al2O3 particles (in spite of a lower stability against grain growth), which is not yet fully understood.

Secondly, some items may be more sensitive to the early stages of cognitive decline and others to the later stages of the disease.

The test measures associative binding with the objective that decrements in the second-list recall would be more sensitive to the early pathological changes associated with preclinical AD.

The by-product of the aforementioned goals will be the identification of ADL-IADL instruments that are highly sensitive to the early stages of disability, and more accurate in detecting change over time.

MRI is more sensitive to the early changes of osteomyelitis because of the excellent contrast between normal and abnormal marrow as well as depiction of surrounding soft tissue changes.

Although many other similar scales were concurrently developed [ 6– 8], the search for a clinical scoring system sensitive to the early pathophysiological changes of DSP reversible by disease-modifying therapy such as aldose reductase inhibitors continues.

Therefore, as we develop tests sensitive to the early cognitive changes associated with biomarker evidence of preclinical AD, we will need to use better approaches for measuring CR or our new tests will need to take into account age, education, sex and race/ethnicity effects on performance, all of which will provide some relative anchoring of an individual's performance vis-à-vis CR.