Sentence examples for sensitive to denaturation from inspiring English sources

The Q4120 antibody recognizes an epitope in the D1 domain of CD4 that is sensitive to denaturation [44].

Although chemical modifications to RNA nucleotides have been shown to be useful in extending the half-life of RNA in the body, RNA secondary structure is still sensitive to denaturation.

Recognition of CXCR4 by four different conformation-dependent antibodies, as well as by CXCL12 and HIV-1 gp120, has been shown to be equivalently sensitive to detergent denaturation of CXCR4 [69], [70], [70].

Though the exact CEACAM1-binding determinants of P5 have not been elucidated, the protein-protein-interaction between the Haemophilus adhesin and its host receptor is sensitive to mild denaturation [51] suggesting again that a specific tertiary or quaternary structure of the complete extracellular domain of CEACAM1 is critical.

Results from these studies indicated that Plin2 tryptophans in the refolded protein were sensitive to urea denaturation.

However, the high G + C composition of this region may render Sakl0C-left as more sensitive to incomplete denaturation.

Although the hypoallergen was folded at +4°C it was more sensitive to thermal denaturation and melted in vitro at a temperature close to normal body temperature.

The latter reflect the efficacy of the denaturant in unfolding and is proportional to the number of groups in the protein, i.e. large proteins are more sensitive to solvent denaturation than small ones [17].

We show that MST instruments allow protein chemical denaturation to be monitored using both fluorescence emission (Fig. 3) and thermophoresis (Fig. 5, see Section 3.2. It is unsurprising that thermophoresis is so sensitive to protein denaturation (Fig. 5 and Fig. S3) since it reports on factors affecting the solvation entropy of proteins [32].

With respect to supersaturated calcium and phosphate solutions, these results would seem to indicate that the calcification-inhibitory influences seen associated with serum are only partially sensitive to heat exposure and that extensive boiling and denaturation are required to effect their inactivation.

The thermal denaturation of native BR is sensitive to alkaline pH.