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This type of trial design allows for the inclusion of highly symptomatic patients providing, in particular, an initially 'greater signal', which would be expected to make it more sensitive to demonstrate a treatment effect.
Second, they evaluated the effects of acute ethanol administration using the T1 relaxation times, to our knowledge, the changes of ADC value are more sensitive to demonstrate water molecular displacement in tissues.
However, given the positive intra-tract relationships shown here, we believe that our tests are sufficiently sensitive to demonstrate a relationship where one exists and therefore are strongly indicative of an absence of inter-tract relationships.
Although one CIN2 was identified at round 2 among baseline HC2−/COBAS+ women, it is possible that the use of only LBC at round 2 was not sufficiently sensitive to demonstrate whether this group of women had underlying CIN lesions not detected by HC2 at baseline.
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Our results suggest that the AOR-index is a sensitive tool to demonstrate how different species respond to particular land-use scenarios.
Although both HOOS and Harris hip score have shown a high degree of validity, it is possible that these instruments are not sensitive enough to demonstrate an underlying difference in clinical outcome between the groups [19, 20].
In a recent study PET in combination with the amino acid analogue [11C]methylaminoisobutyrate were sensitive enough to demonstrate an enhanced amino acid transport in human skeletal muscle during euglycaemic hyperinsulinaemic clamping [34].
The DEX/CRH test at present is considered to be the most sensitive tool to demonstrate a disturbed regulation of the HPA axis in depressed patients and has been shown to have a sensitivity of more than 80% if subjects are clustered into different age ranges [25].
These techniques have been shown to be sensitive enough to demonstrate acute changes in human cartilage dGEMRIC [ 42, 67] and T2-relaxation times [ 42, 136].
The original survey was difficult to administer without interfering with patient flow in the clinic and additionally, many scales were not sensitive enough to demonstrate changes over time.
Giemsa stained blood smear examination is not a sensitive method to demonstrate parasites in the blood mainly because of the periodically cryptic nature of the parasite.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com