Sentence examples for sensitive to block from inspiring English sources

In particular: 1) eCBmGluR is much less sensitive to block by DAGL-inhibitors than is DSI, and 2) repetitive activation of the eCBmGluR system enhanced the effect of DAGL inhibition, whereas such use-dependence was not a feature of the block of DSI.

Membrane depolarization induced by elevation of K+ has been previously shown to induce vasoconstriction of the SMA, which is sensitive to block of L-type VDCCs [ 30].

That TPC2 may confer mechanosensitive Ca2+ signals and be sensitive to block by VGCC antagonists also has resonance with respect to the myogenic response of arterial smooth muscle and related vascular pathophysiology.

However, quantitatively, hiPSC-CMs were more sensitive to block of (i) L-type Ca2+ currents due to the overexpression of the Na+/Ca2+ exchanger (leading to shorter APs) and (ii) the inward rectifier K+ current due to reduced repolarization reserve (inducing diastolic potential depolarization and repolarization failure).

The acquisition of conditioned responding is sensitive to blocking, indicating that predicton errors play a role in the acquisition of dopamine responses to conditioned stimuli [ 27].

Again ORF23 is co-expressed with tertiary lytic ORFs [ 25] and is sensitive to blocked DNA replication [ 27], so it is a late gene.

CD47 is key to protecting red blood cells from macrophages, and red blood cells are particularly sensitive to the blocking effects of the antibody as they get older, Leeper says.

All other Kv channel species tested (Mouse Kv1.1, rat Kv1.2, human Kv1.5 and mouse Kv3.1 [34] proved considerably less sensitive to clofazimine, blocking less than 50% of current at a 10 µM concentration (Fig. S4).

NCC is responsible for apical Na+ and Cl− entry into distal convoluted tubule cells and is sensitive to thiazide blocking [ 59, 60].

ERα-positive breast cancers rely on estrogen signaling for proliferation, and hence the most effective strategy to stop or slow the growth of these hormone-sensitive tumors is to block estrogen action in the tumor using endocrine therapy.

Simulation results therefore reflect the fact that APD90 using our human model is more sensitive to ICaL block than to IKr block for a similar drug dose with respect to the IC50.