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One neuronal function that is particularly sensitive to altered P/Q signaling is the precise timing of spikes.
According to Ganzhorn and Schmid [ 63], the species is extremely sensitive to altered environmental conditions.
Stimulus-specific putamen/pallidal responses in obese people with binge eating are sensitive to altered mu-opioid function.
Androgens are critical for specifying prostate development, with the fetal prostate sensitive to altered hormone levels and endocrine-disrupting chemicals (EDCs) that exhibit estrogenic or antiandrogenic properties.
Alternatively, phenotypes arising from genes whose function is sensitive to altered copy number will incur an ascertainment bias of these deletions.
Cells of the immune system are highly sensitive to altered gravity, and the monocyte as well as the macrophage function is proven to be impaired under microgravity conditions.
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L. mexicana will also infect mice, and although the immunological factors determining resistance and susceptibility are not as well-defined as in L. major [ 24- 26], it offers the advantage of slower in vivo kinetics and consequently is anticipated to be more sensitive to altering factors.
Results from previous animal studies show that, during that reconsolidation, memories are sensitive to being altered or even erased.
Any tissue sensitive to this altered transgenerational transcriptome will have a susceptibility to develop disease [ 23].
It is sensitive to discover altered glycans as promising markers at glycosylation levels.
These defects may be due to altered ATP-sensitive K+ (KATP) channel subunit expression, and we found that Kcjn11 expression was significantly increased in POMCS6K1KO and reduced in AgRPS6K1KO when compared with WT mice; however, Abcc9 expression was unchanged.
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