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If we could determine the most sensitive time frame for these two chemicals, we might not need to find a counteractive drug.
Although the preimplantation period might be a sensitive time frame for BPA and TCS exposure, it might not be the most sensitive and important one.
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Proof of human effects is very difficult to achieve because the damage may be made during very limited, sensitive time frames of development.
Fortunately, the pharmacokinetic features of these two chemicals suggest that the fertility rate of women could probably be raised just by minimizing contact with BPA -and TCS-containing products during sensitive time frames such as the preimplantation period.
The thing about goals is they are time sensitive, so adding a time frame helps you to accept the fact that you are committed to doing it.
The concentration of vinflunine required to induce PARP degradation and DNA fragmentation in the P388/VFL cells, with a 17-fold level of resistance to vinflunine, was 10-fold higher than that required to induce the same effects in sensitive cells within the same time frame.
According to the authors, the combined strategy is likely to be the optimum strategy, but results were highly sensitive with regard to the applied time frame.
The time frame of the sensitive period may be different for drug or noise insult to the cochlea, but the principal pathology of outer hair cell loss remains the same in both cases.
The two techniques are less sensitive for protein segments moving in a time frame of microseconds to milliseconds.
There were eight measures used primarily within a six month period, suggesting they might be more sensitive to change in a relatively short time frame.
Larvae are sensitive to olfactory cues of kin individuals in a specific time frame during development, in which imprinting on kin odours may occur.
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CEO of Professional Science Editing for Scientists @ prosciediting.com