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Notably, the sensitivity of brain CT for subarachnoid hemorrhage approaches almost 100%% within the first hours, while the sensitivity of lumbar puncture with detection of bilirubin and MRI with hemosiderin sensitive sequences increases with time [23].
Important small vessel disease markers are: 1. Cerebral microbleeds, seen as punctate foci of hypointensity on susceptibility sensitive sequences.
Any disease process leading to an increased amount of fluid will show increased signal on the fluid sensitive sequences (T2 fat sat and STIR) and decreased signal in T1w images.
Furthermore, considering the limitation of conventional T2* GRE sequences, which have underestimated MBs in 25%% of CAA patients, more sensitive sequences such as SWI and PRESTO sequences should be used to increase the detection rates of MBs (Fig. 1) [9].
The importance of the proteolytic activity of cells has been already considered in the design of biomaterials by incorporating MMP sensitive sequences, which have shown to be mandatory in tissue regeneration in 3D, including cell proliferation, migration and angiogenesis [62] [65].
The enhanced accuracy is probably the result of the automated preselection of one of the five most sensitive sequences in the estimated liver iron concentration range.
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The precise control of the formation of stimuli-sensitive sequences (block or graft) as part of copolymer architectures is fascinating because of the remarkable phase behavior of their aqueous solutions.
GFP mutants engineered with trypsin-sensitive sequences close to the eosin site, so that on trypsinolysis FRET was destroyed, the emission wavelength switching from that of the chemical FRET partner back to that of the native GFP fluorophore, providing efficient, ratio-based detection.
In healthy individuals, the PF is homogeneously hypointense on both T1-weighted and fluid-sensitive sequences [6].
The shoulder is studied in three planes (i.e., axial, oblique coronal, oblique sagittal) with fat-suppressed (FS) fluid-sensitive sequences (proton density (PD) or T2 weighted).
Fluid-like hyperintensity on fluid-sensitive sequences such as short tau inversion recovery (STIR) and spectral presaturation with inversion recovery (SPIR) favors the cystic nature of the lesion.
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